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  • ICAR and TNAU E-Course Summarized

    Summarized Notes
  • Which one of the following statements about histones is wrong?

    Question: Which one of the following statements about histones is wrong?

    Options:

    Histones carry positive charge in the side chain
    Histones are organized to form a unit of 8 molecules
    The pH of histones is slightly acidic
    More than one of the above

    📌 Concept:
    DNA is a double helical molecule that is negatively charged due to the presence of phosphates in them.
    To stabilize the negative charge, histone proteins bind the DNA.

    ✅ Explanation:
    Histones are positively charged, basic proteins (basic pH) that stabilizes the DNA or chromatin.
    They are made up of mainly lysine and arginine amino acids which are positively charged amino acids.
    Eight histone proteins combined and form histone octamer.
    It consists of histones two copies of each of the 4 core histone proteins, that is, H2A, H2B, H3, and H4.
    H1 histone is another histone protein that links the histones in an octamer. It is also known as linker histone.

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