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  • ICAR and TNAU E-Course Summarized

    Summarized Notes
  • Which of the following amino acids contains a positively charged side chain at a pH of 7.0?

    Question: Which of the following amino acids contains a positively charged side chain at a pH of 7.0?

    Options:

    Glutamic acid
    Arginine
    Tyrosine
    None of these

    ✅Explanation:
    At a physiological pH of 7.0, the side chains of amino acids can be charged depending on their pKa values. Arginine has a positively charged side chain at this pH because its guanidinium group remains protonated.

    📌Other Options Explanation:

    a) Glutamic acid:
    -Glutamic acid has a negatively charged side chain at pH 7.0 because its carboxylic acid group is deprotonated (pKa ~4.3).

    (c) Tyrosine:
    -Tyrosine has a phenolic hydroxyl group in its side chain, which has a pKa ~10.1. At pH 7.0, this group remains neutral.

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