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  • ICAR and TNAU E-Course Summarized

    Summarized Notes
  • The nucleosome-solenoid model of chromatin structure was proposed by which of the following?

    Question: The nucleosome-solenoid model of chromatin structure was proposed by which of the following?

    Options:

    DuPraw
    Komberg and Thomas
    Whitehouse and Holliday
    Darlington

    ✅Explanation:
    -The nucleosome-solenoid model of chromatin structure was proposed by Roger Kornberg and John Thomas in 1974. This model suggests that chromatin is organized into a series of nucleosomes, which are bead-like structures made up of DNA wrapped around a core of histone proteins. The nucleosomes are then further organized into a solenoid structure, which is a spiral-shaped fiber.

    12Other options explanations:
    -DuPraw: Proposed the folded-fiber model of chromosome structure.
    -Whitehouse and Holliday: Proposed the "two-start" model of the 30 nm chromatin fiber.
    -Darlington: Developed the pachytene pairing hypothesis of chromosome synapsis.

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