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  • ICAR and TNAU E-Course Summarized

    Summarized Notes
  • The distribution pattern of saliva by the silkworm is…? (IFFCO 2022)

    Question: The distribution pattern of saliva by the silkworm is…? (IFFCO 2022)

    Options:

    Sex-linked recessive disorder
    Autosomal dominant disorder
    Autosomal recessive disorder
    Sex-linked dominant disorder

    ✅Explanation:
    Cystic fibrosis (CF) is an inherited disease that primarily affects the lungs and digestive system. It is caused by a mutation in the CFTR gene, which codes for a protein that regulates the movement of salt and water in and out of cells. Here's why it's classified as autosomal recessive:  
    -Autosomal: The CFTR gene is located on chromosome 7, one of the 22 pairs of autosomes (non-sex chromosomes). This means the inheritance pattern is not linked to the sex of the individual.
    -Recessive: Two copies of the mutated CFTR gene (one from each parent) are needed to have CF. If a person has only one mutated copy, they are a carrier but do not have the disease.
    🔑Key Points:-
    -Cystic fibrosis is an inherited life-threatening disorder that damage the lungs and digestive system
    -Cystic fibrosis affects the cell that produce mucus, sweat, digestive juices, It is causes fluid become thick and sticky.
    -Cystic fibrosis is caused by a change in (mutation) in the gene that makes cystic fibrosis it is known as autosomal recessive disease
    -Autosomal recessive disorder have one changed gene (recessive gene) and one unaffected gene (dominant gene) for condition.
    -An autosomal recessive disorder means two copies of abnormal gene must be present in order for the disease or trait.
    -Unaffected parent are called carries because they each carry one copy of muted gene and can pass it to their children.

    🛑Additional Information:
    -X linked dominant disorder ->  it refers to genetic condition associated with mutation in genes on the X chromosome
    -Autosomal dominant disorder -> autosomal dominant is one of many ways that a trait or disorder can be passed down through families.
    -X linked recessive disorder -> it is refers to genetic condition associated with mutation in genes on the X chromosome.

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