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  • ICAR and TNAU E-Course Summarized

    Summarized Notes
  • Phagocytosis is discovered by

    Question: Phagocytosis is discovered by

    Options:

    Robert Koch
    Elie Metchnikoff
    Joseph Lister
    Fanny Hesse

    ✅Explanation:
    -Elie Metchnikoff, a Russian zoologist and immunologist, is credited with the discovery of phagocytosis in 1882.
    -He observed that certain cells in starfish larvae engulfed and destroyed foreign particles, a process he named phagocytosis (from the Greek words "phagein" meaning to devour and "kytos" meaning cell).
    -This discovery laid the foundation for understanding the cellular basis of immunity and the role of white blood cells in defending the body against infections.

    🔑Key Points:
    Phagocytosis
    -Phagocytosis is the process of engulfment and destruction of solid particles such as bacteria, dead tissue and foreign particles by the cells.
    ​Phagocytes
    – The cells performing phagocytosis are called phagocytes
    -The cells are
    -​Neutrophil
    -Macrophage
    -Monocytes
    ​Neutrophil
    – Neutrophils are the most abundant type of granulocytes.
    -They are composed of 40-70 percent of WBC.
    -They are formed from the stem cells in the bone marrow
    -Major functions are
    -​Chemotaxis
    -Anti-microbial function
    -Phagocytosis by antibody opsonization
    -Degranulation
    Eosinophils
    -Along with mast cells and basophils, they also control mechanisms associated with allergic reactions.
    -Formed in the bone marrow
    -Composed of 2-3 percent in WBC
    ​Polymorphs
    -Polymorphonuclear (PMN) cells refer to the group of white cells known as granulocytes.
    – That includes neutrophils, eosinophils, basophils, and mast cells.
    -PMNs are a subtype of leukocytes.
    ​Basophils
    -Basophils are a type of white blood cell
    -Representing about 0.5% to 1% of circulating white blood cells.

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