Question: In mitosis, the longest phase is:
Options:
Prophase
Metaphase
Anaphase
Telophase
Prophase is indeed the longest phase of mitosis, typically consuming 50-70% of the total cell division time. During prophase, several crucial events occur:
-Chromatin condensation:Â Chromosomes become tightly coiled and visible under a microscope.
-Nuclear envelope breakdown:Â The nuclear envelope surrounding the chromosomes disintegrates.
-Formation of the mitotic spindle:Â Microtubule fibers assemble to form the spindle apparatus, which will later separate the sister chromatids.
-Centrosome duplication and migration:Â Centrosomes, involved in spindle organization, duplicate and move to opposite poles of the cell.
-Pairing of homologous chromosomes:Â Homologous chromosomes (those with the same genes from each parent) come together and pair up.
-Crossing over:Â In some organisms, genetic material is exchanged between homologous chromosomes during this phase.
The other phases of mitosis are:
-Metaphase:Â Shortest phase, characterized by chromosomes aligned at the equator of the cell, ready for separation.
-Anaphase:Â Sister chromatids separate and move towards opposite poles.
-Telophase:Â Nuclear envelopes reform around the separated chromosomes, and the cell starts dividing into two daughter cells.
⚡Related Terminology:
-Mitosis:Â Cell division process where one cell divides into two genetically identical daughter cells.
-Sister chromatids:Â Identical copies of a chromosome, held together by centromeres.
-Homologous chromosomes:Â Chromosomes with the same genes from each parent.