Question: Fatty acid synthesis requires ……………..
Options:
NAD
NADPH
TPP
FAD
📌 Other Options Explanations:
-(A) NAD: NAD is an oxidizing agent involved in catabolic processes (energy generation).
-(C) TPP: Thiamine pyrophosphate (TPP) is a cofactor involved in carbohydrate metabolism.
-(D) FAD: Flavin adenine dinucleotide (FAD) is an oxidizing agent involved in energy generation.
🔑Key Points:
-The fatty acids are synthesized with starting material as Acetyl CoA and NADPH in the presence of enzyme fatty acid synthases.
-The NADPH required for this process of fatty acid biosynthesis comes from oxidative decarboxylation of malate.
-Malate gets oxidized to pyruvate and CO2, and NADP+Â gets reduced to NADPH.