At a specific temperature, the number of minutes required to destroy the desired number of cells of any microbe is

• F- Value:
It is the process in which a number of minutes are required to kill a known population of microorganisms in specified condition i.e 121.1ºC (TDT)
The F-Values are mostly set at 12 D values. When Z value of the process is 10ºC, F is denoted as Fo(integrated heating effect received by all points)

🔴Additional Information::
D-value can be done by 2 methods 
-survivor method
-fraction negative method
Z=T1−T2/log⁡D1−log⁡D2
Z-value: it is the temperature in degrees that is required for the thermal destruction curve to move one log cycle.
Z-value: is a measure of change of D value with varying temperatures.
The range is 10-15ºC.
T-value: it is TDT thermal death time that is necessary to kill a specific number of microbes at a specific temperature.