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  • ICAR and TNAU E-Course Summarized

    Summarized Notes
  • Proteins that bind to TATA box in promoter region are

    Question: Proteins that bind to TATA box in promoter region are

    Options:

    (a) Coactivators
    (b) Coregulators
    (c) Enhancers
    (d) Transcriptional factors

    ✅ Explanation: Transcription factors are proteins that bind to specific DNA sequences, such as the TATA box, in the promoter region of a gene. This binding helps to initiate the process of transcription, where the DNA sequence is copied into RNA.

    🔑Key Points :
    The TATA box is a DNA sequence commonly found in the core promoter region of genes in eukaryotes and archaea. It serves as a crucial binding site for transcription factors and RNA polymerase II, which are necessary for the initiation of transcription. The consensus sequence for the TATA box is TATAWAW, where "W" represents either adenine (A) or thymine (T).
    -Shine-Dalgarno sequence: Found in prokaryotic mRNA, it is essential for the initiation of translation, not transcription. It helps in the binding of the ribosome to the mRNA.
    -TATA box: As described above, this is the correct option for eukaryotic promoters
    -Pribnow box: This is found in the promoter region of bacterial DNA, analogous to the TATA box in eukaryotes, but with a shorter consensus sequence (TATAAT).
    -3' UTR: This is the 3' untranslated region of mRNA, important for post-transcriptional regulation but not involved in the initiation of transcription

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