In which cellular compartment does the Krebs cycle occur?

✅Explanation: The Krebs cycle (also known as the citric acid cycle or tricarboxylic acid cycle) occurs in the mitochondrial matrix. This cycle is a critical part of cellular respiration, where acetyl-CoA is oxidized to produce energy in the form of ATP, NADH, and FADH₂.

📌📌Other Options:
-(a) Mitochondrial membrane: The mitochondrial membrane is involved in the electron transport chain.
-(b) Cytoplasm: The cytoplasm is the fluid inside the cell, outside the mitochondria.

🛑Aditional Information:
-The Krebs cycle occurs in the matrix of mitochondria. In this process, pyruvic acid is fully oxidized and converted into CO2 and H20.
Krebs Cycle / Tricarboxylic Acid Cycle / Citric Acid Cycle – 
-The TCA cycle starts with the condensation of the acetyl group with oxaloacetic acid (OAA) and water to yield citric acid.
-The reaction is catalysed by the enzyme citrate synthase and a molecule of CoA is released.
-Citrate is then isomerised to isocitrate.
-It is followed by two successive steps of decarboxylation, leading to the formation of α-ketoglutaric acid and then succinyl-CoA.
-In the remaining steps of the citric acid cycle, succinyl-CoA is oxidised to OAA allowing the cycle to continue.
-During the conversion of succinyl-CoA to succinic acid, a molecule of GTP is synthesised. This is substrate-level phosphorylation.
-In a coupled reaction GTP is converted to GDP with the simultaneous synthesis of ATP from ADP.
-Also, there are three points in the cycle where NAD+ is reduced to NADH+ H+ and one point where FAD+ is reduced to FADH2.
-The continued oxidation of acetyl CoA via the TCA cycle requires the continued replenishment of oxaloacetic acid, the first member of the cycle.
-In addition, it also requires regeneration of NAD+ and FAD+ from NADH and FADH2 respectively.