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  • ICAR and TNAU E-Course Summarized

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  • Colchicine is primarily obtained from which part(s) of the plant: (JRF Plant Science 2021)

    Question: Colchicine is primarily obtained from which part(s) of the plant: (JRF Plant Science 2021)

    Options:

    Root
    Shoot apex
    Mature leaves
    Corm and seeds

    ✅Explanation: Colchicine is a valuable alkaloid drug with medicinal and research applications. It is primarily obtained from the Colchicum autumnale plant (commonly known as autumn crocus or meadow saffron).• Corm: The corm is the swollen underground stem of the plant. It is a major source of colchicine.• Seeds: The seeds of Colchicum autumnale also contain significant amounts of colchicine.
    🔑Key Points:• Colchicine, a mitotic poison, is obtained from a plant, Colchicum autumnale. This plant is commonly known as autumn crocus, meadow saffron.• The seed, bulb, and flower are used to make medicine. The appropriate dose of autumn crocus depends on several factors such as the user's age, health, and several other conditions.• All parts of autumn crocuses are poisonous, with the greatest concentrations of toxic alkaloids occurring in the flowers and seeds. The primary toxic alkaloid is colchicine, which interferes with cell mitosis.• Colchicine and its related alkaloids interfere with microtubular-dependent cell functions by binding to tubulin protein, thus blocking mitosis in multiple tissues. All animals are susceptible to the toxic effects of colchicine.
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