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  • ICAR and TNAU E-Course Summarized

    Summarized Notes
  • Mad cow disease in the cattle is caused by

    Question: Mad cow disease in the cattle is caused by

    Options:

    Virus
    Viroid
    Prions
    Bacteriophage

    🔑 Explanation
    → The bovine spongiform encephalopathy (BSE), commonly called "mad cow disease" in cattle, and its analogous variant Cr–Jacob disease (CJD) in humans is caused by prions.
    → Prions are infectious agents similar in size to viruses that cause the transmission of several infectious neurological diseases.
    → These differ from viruses by having an abnormally folded protein.
    → Prions were named by Stanley Prusiner.

    📌 Important Points
    → Mad cow disease is a progressive neurological disorder in which cattle experience trouble while walking, weight loss, and show abnormal behaviour.

    📝 Additional Information
    → Virus:
    → Viruses are non-cellular organisms characterised by an inert crystalline structure outside the living cell.
    → The name virus, meaning venom or poisonous fluid, was given by Dmitri Ivanowsky (1892).
    → Viruses are largely made up of proteins, and also contain genetic material, which could be either RNA or DNA.
    → Viruses cause diseases like mumps, smallpox, herpes, and influenza. AIDS in humans is also caused by a virus. In plants, symptoms can include mosaic formation, leaf rolling, yellowing, vein clearing, dwarfing, and stunted growth.

    → Viroid:
    → Viroids are infectious agents that consist of nucleic acid (ssRNA) in their genome but lack a protein coat.
    → Viroids were first discovered by T.O. Diener (1971), who observed that these were smaller than viruses and caused potato spindle tuber disease.

    → Bacteriophage:
    → A bacteriophage is a virus that infects bacteria.
    → Bacteriophage was discovered by Twort & Felix.
    → A bacteriophage consists of proteins that encapsulate a DNA or RNA genome.

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